Merosin Deficiency Congenital Muscular Dystrophy. It affects the Laminin alpha chain 2.
The basics of this condition: It is NOT a leukodystrophy (white matter brain disease). Instead, it's a Muscular Dystrophy. The old diagnosis had a prognosis of about age 2. This one is "rarely makes it to adolescence". This is NOT typically regressive (and since his hasn't regressed since birth, the odds are very low that he would lose functions). It spares cognitive function. These kids typically die of respiratory complications. (Their lung function just can't keep up with their body growth, they get sick and don't recover.) Typically they do not ever walk. They tend to contractures (tightness) in ankles, hips and elbows. (Manny has the ankle). Also tend to develop sciolosis.
So ... overall, not the greatest thing to have. It is a very "life shortening" condition.
The good news? I have a big and mighty God. He loves Manny. He hears prayers. We are still in faith that this story's ending isn't written yet. Doctors have gotten it "wrong" before. God has the final say.
I KNOW that Manny is supposed to be on this Earth. He has jobs to do. They are not completed yet.